Chest Pain
High Risk Indicators-Perfusion Imaging
- Increased pulmonary thallium uptake indicating low CO or elevated
LVEDP
- Ischaemic LV dilatation
- Multiple perfusion defects
- Large perfusion defects
Comparing Perfusion Agents
- Thallium-201
- K analogue
- uptake proportional to blood flow
- washes out slowly from myocardium-redistribution phase
- defect normalizes = ischaemia
- defect unchanged = scar
- ?Tl lung uptake- indicates ischaemic LV dysfunction
- ischaemic LV dilatation on post exercise scan = high risk indicator
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- uptake proportional to blood flow
- tissue uptake is fixed
- higher energy/better tissue penetration and images
- tissue fixation permits gated LV Angiogram
- wall motion
- ejection fraction
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Sensitivity and Specificity of Myocardial Perfusion Imaging for CAD
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