Atrial Fibrillation











Decision Aide

The information about the likelihood of stroke over one year that is provided will depend upon your risk factors. Risk factors for stroke in atrial fibrillation include: age, hypertension (HTN), diabetes (DM), congestive heart failure (CHF) and prior stroke (CVA) or transient ischaemic attack (TIA). The table presents the risk of stroke over one years of follow-up stratified by age and risk factors. Guideline recommendations are based on the Sixth (2000) ACCP Guidelines for Antithrombotic Therapy for Prevention and Treatment of Thrombosis (CHEST 2001; 119, supplement)

Warfarin (Coumadin“) therapy requires frequent blood monitoring of prothrombin time (PT) or INR. Patients with atrial fibrillation require an INR optimally of 2.5 (range between 2 and 3). Coumadin dose is adjusted according to blood tests to maintain the INR in the therapeutic range.


Patients with atrial fibrillation and structural heart disease: hypertensive heart disease, coronary heart disease with LV dysfunction, rheumatic valvular heart disease, congenital valvular heart disease (bicuspid aortic valve with AS, MVP), hypertrophic cardiomyopathy (obstructive or non-obstructive), idiopathic dilated cardiomyopathy or complex congenital heart disease are at high risk for stroke.

Decision:    No anti-thrombotic Rx      ASA      Warfarin

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  Version 2.0, January 2005
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