DISCLAIMER:

n the currently posted Lipid Optimization Tool the UPPER STRATUM: CAD, PCI, CABG, TIA/CVA, PVD/bruits, DM (Age > 30) exceeds the 2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult - 2009 recommendations. 

Consider more aggressive therapy to a LDL target < 1.8 mmol/L in these populations based on HPS , AVERT , MIRACL, REVERSAL, PROVE-IT and TNT.

Revised NCEP-ATP III Guidelines  include a discretionary LDL target of <70 mg/dL (1.8 mmol/L) for very high risk patients. Circulation. 2004;110:227-239.