Cholesterol

Statin Cost Efficacy

The Statin Cost Efficacy Grid details the cost and LDL lowering efficacy of all currently available statins. Statins and doses are highlighted based on evidence or cost efficacy. The green column highlights the minimum therapeutic bar for treatment of low and moderate risk patients. The orange column highlights the minimum therapeutic bar to halt atherosclerotic progression. The pink column highlights the minimum therapeutic bar for treatment of high risk patients or patients with atherosclerotic risk equivalents. The bright orange column highlights the minimum therapeutic bar to induce atherosclerotic regression. See the Lipid Optimization Tool for the therapeutic protocol.

The 2009 CCS/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascuar disease in the adult
(Can J Cardiol Vol 25 No 10 October 2009) recommends targeting LDL reduction to ≥ 50% when treating any level of cardiovascular risk
with pharmacotherapy. Initiation thresholds vary depending on level of risk and presence of risk modifiers.

This chart is available for download as a PDF in the Downloads section.

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